{"version":2,"kind":"Article","sha256":"","slug":"142","location":"","dependencies":[],"frontmatter":{"title":"Cellular senescence promotes progenitor cell expansion during axolotl limb regeneration","abstract":"Cellular senescence in axolotl limb regeneration promotes progenitor cell growth and blastema development via Wnt pathway modulation, as revealed by gain- and loss-of-function studies. This senescence creates a pro-proliferative environment, preventing neighboring cells from becoming senescent.","license":"CC BY","keywords":[],"authors":[{"name":"Qinghao Yu","orcid":"","affiliations":[],"corresponding":true},{"name":"Hannah E. Walters","orcid":"","affiliations":[],"corresponding":true},{"name":"Giovanni Pasquini","orcid":"","affiliations":[],"corresponding":true},{"name":"Sumeet Pal Singh","orcid":"0000-0002-5154-3318","affiliations":[],"corresponding":true},{"name":"Martina Lachnit","orcid":"","affiliations":[],"corresponding":true},{"name":"Catarina Oliveira","orcid":"","affiliations":[],"corresponding":true},{"name":"Daniel León-Periñán","orcid":"","affiliations":[],"corresponding":true},{"name":"Andreas Petzold","orcid":"","affiliations":[],"corresponding":true},{"name":"Preethi Kesavan","orcid":"","affiliations":[],"corresponding":true},{"name":"Cristina Subiran","orcid":"","affiliations":[],"corresponding":true},{"name":"Ines Garteizgogeascoa","orcid":"","affiliations":[],"corresponding":true},{"name":"Dunja Knapp","orcid":"","affiliations":[],"corresponding":true},{"name":"Anne Wagner","orcid":"","affiliations":[],"corresponding":true},{"name":"Andrea Bernardos","orcid":"","affiliations":[],"corresponding":true},{"name":"María Alfonso","orcid":"","affiliations":[],"corresponding":true},{"name":"Gayathri Nadar","orcid":"","affiliations":[],"corresponding":true},{"name":"Alwin M. Graf","orcid":"","affiliations":[],"corresponding":true},{"name":"Konstantin E. Troyanovskiy","orcid":"","affiliations":[],"corresponding":true},{"name":"Andreas Dahl","orcid":"0000-0002-2668-8371","affiliations":[],"corresponding":true},{"name":"Volker Busskamp","orcid":"","affiliations":[],"corresponding":true},{"name":"Ramón Martínez-Máñez","orcid":"","affiliations":[],"corresponding":true},{"name":"Maximina H. Yun","orcid":"0000-0001-9019-2453","affiliations":[],"corresponding":true}],"date_submitted":"2023-12-14T00:22:24.000Z","external_publication_id":142,"revision_cids":["bafkreidll4iaylvaplqqqotp3e7bolx3qgqnjkzliplbhdz7v7dcrdn65q","bafkreieszmyc5ph43ft77gk4pj5emhuy53if6vjbeejzxbrtusxb3ouq54"]},"mdast":{"type":"root"},"references":{"cite":{"order":[]},"data":{}}}